Characterization of Proteus mirabilis Precocious Swarming Mutants: Identification of rsbA , Encoding a Regulator of Swarming Behavior
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چکیده
منابع مشابه
Urea restrains swarming of Proteus mirabilis.
In veterinary microbiology, samples taken from ears or wounds of dogs and cats are often contaminated by Proteus mirabilis. P. mirabilis swarms over the entire plate culture of these samples, making it almost impossible to isolate single colonies of other bacterial species present in the sample. Various compounds, like p-nitrophenyl glycerin and activated charcoal, abolish the swarming of Prote...
متن کاملModulation of swarming and virulence by fatty acids through the RsbA protein in Proteus mirabilis.
After sensing external signals, Proteus mirabilis undergoes a multicellular behavior called swarming which is coordinately regulated with the expression of virulence factors. Here we report that exogenously added fatty acids could act as signals to regulate swarming in P. mirabilis. Specifically, while oleic acid enhanced swarming, some saturated fatty acids, such as lauric acid, myristic acid,...
متن کاملTheory of periodic swarming of bacteria: application to Proteus mirabilis.
The periodic swarming of bacteria is one of the simplest examples for pattern formation produced by the self-organized collective behavior of a large number of organisms. In the spectacular colonies of Proteus mirabilis (the most common species exhibiting this type of growth), a series of concentric rings are developed as the bacteria multiply and swarm following a scenario that periodically re...
متن کاملSwarming-coupled expression of the Proteus mirabilis hpmBA haemolysin operon.
The HpmA haemolysin toxin of Proteus mirabilis is encoded by the hpmBA locus and its production is upregulated co-ordinately with the synthesis and assembly of flagella during differentiation into hyperflagellated swarm cells. Primer extension identified a sigma(70) promoter upstream of hpmB that was upregulated during swarming. Northern blotting indicated that this promoter region was also req...
متن کاملRegulation of the swarming inhibitor disA in Proteus mirabilis.
The disA gene encodes a putative amino acid decarboxylase that inhibits swarming in Proteus mirabilis. 5' rapid amplification of cDNA ends (RACE) and deletion analysis were used to identify the disA promoter. The use of a disA-lacZ fusion indicated that FlhD(4)C(2), the class I flagellar master regulator, did not have a role in disA regulation. The putative product of DisA, phenethylamine, was ...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1998
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.180.23.6126-6139.1998